We have a new paper published in Journal of Physical Chemistry Letters on “Single Molecule Surface Enhanced Raman Scattering in a Single Gold Nanoparticle-Driven Thermoplasmonic Tweezer”
Thanks to the fantastic effort by Sunny Tiwari, and excellent support by Utkarsh Khandelwal (former IISER-P undergrad) and Vandana Sharma from my group, we have been able to combine single molecule Raman scattering with a specialized nanoscale optical tweezer.
The uniqueness of this tweezer platform is that the optical trapping process is driven by the thermo-plasmonic potential created by a SINGLE, 150nm GOLD NANOPARTICLE. Concomitantly, the same field can be used to perform single-molecule Raman spectroscopy. Kind of “ek teer mae do shikar” strategy
Using this system, not only we push the limits of optothermal trapping of a single nanoparticle (see video) at low laser powers, but also create a platform for deterministic transport of reversible colloidal assembly in a fluid.
We envisage that our nanometric plasmonic tweezer can be harnessed to trap and tweeze biological entities such as single virus and bacteria. Another possible application of our study is to create reconfigurable plasmonic metafluids in physiological and catalytic environments, and to be potentially adapted as an in vivo optothermal tweezer.
All the videos related to this study can be found on our lab’s Youtube channel : https://www.youtube.com/playlist?list=PLVIRTkGrtbrvs7BaNsaH6tjPpzLUizyMI
DoI of the published paper : https://doi.org/10.1021/acs.jpclett.1c03450
preprint version on arxiv : https://arxiv.org/abs/2109.04281